Yana Vinogradova wanted to know what happens to the bones of women who withdraw from hormone replacement therapy or HRT—a common strategy when patients no longer have hot flashes or quit taking the drug for other reasons.
A mathematician and HRT researcher at the University of Nottingham, Vinogradova was inspired to mine primary care data for answers after a friend told her she planned to take HRT. Her friend had no hot flashes or other symptoms but was compelled by the evidence that bones are stronger in postmenopausal women who are on HRT.
