Too much synthetic folic acid from supplements and fortified foods may harm brain development and could be involved in rising rates of neurodevelopmental disorders in children.
Story at a Glance
- It’s extremely rare to get too much folate from foods, but it is possible to get too much folic acid, the synthetic version of folate found in supplements and fortified foods.
- In pregnant mice, high levels of folic acid harmed brain development in offspring, and low levels of vitamin B12 made the damage worse.
- The combination of low vitamin B12, which often occurs in people eating vegan or vegetarian diets, along with high folic acid, could be increasing neurodevelopment disorders in children.
- Due to prenatal supplements and fortified foods, many people have abnormally high levels of folic acid.
- Studies looking into the effects of folic acid on autism development are conflicting, with some showing a protective effect, but a growing body of evidence points to potential harms when consumed in excess.
Dr. Joseph Mercola is the founder of Mercola.com. An osteopathic physician, best-selling author, and recipient of multiple awards in the field of natural health, his primary vision is to change the modern health paradigm by providing people with a valuable resource to help them take control of their health.
Author’s Selected Articles





