A new animal study published in the journal PLoS sheds light on a possible mechanism behind the weight- and diabetes-promoting properties of wheat observed in humans, and perhaps offers some vindication for Dr. William Davis’ New York Times best-selling but heavily criticized book ‘Wheat Belly,’ wherein the argument is made that wheat is a major contributing factor to the epidemic of obesity and diabetes presently afflicting wealthier, gluten-grain consuming nations.
In the new study, researchers from The Bartholin Institute, Copenhagen, Denmark, explored the role that gliadin, a difficult to digest class of proteins within wheat, plays in promoting weight gain and insulin secretion in both animal and cell models, finding that gliadin-treated mice gained 20% more weight (by day 100) than gliadin-free controls, and that gliadin fragments induce insulin secretion in pancreatic beta cells, the cells responsible for producing insulin, and which in type 1 diabetes are destroyed or rendered dysfunctional.
