Statins and GLP-1s: Two Blockbuster Drugs, One Overlooked Problem

What to do when a blockbuster drug for one condition disrupts the hormone behind another blockbuster drug: a case of informed consent.
Statins and GLP-1s: Two Blockbuster Drugs, One Overlooked Problem
Statins appear to undermine GLP-1, the hormone behind Ozempic and Wegovy. Why isn't anyone talking about it? Illustration by The Epoch Times/Shutterstock
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For decades, statins have been prescribed to tens of millions of Americans to lower cholesterol and ward off heart disease. Today, about one in three adults take them.
However, a 2024 study published in Cell Metabolism suggests these drugs may quietly disrupt another part of the body’s metabolism. Patients on atorvastatin, one of the most common statins, saw their levels of GLP-1—the hormone mimicked by Ozempic and other weight-loss drugs—drop by nearly half.
Sheramy Tsai
Sheramy Tsai
Author
Sheramy Tsai, BSN, RN, is a seasoned nurse with a decade-long writing career. An alum of Middlebury College and Johns Hopkins, Tsai combines her writing and nursing expertise to deliver impactful content. Living in Vermont, she balances her professional life with sustainable living and raising three children.