Nitric oxide (NO) is one of the most important signaling molecules in our body and is involved in virtually every organ system. Some researchers say that there’s a very clear progression of cardiovascular disease that begins with decreased NO production.
Every age-related disease and every chronic disease—whether it manifests in the kidney, brain, heart, or liver—has a vascular component, according to Nathan S. Bryan, an international leader in molecular medicine and NO biochemistry. Bryan says that the common trait among them is a lack of oxygen-rich blood reaching a part of the body, and this is dependent on NO.





