An animal study published in the journal Brain, Behavior, and Immunity found that a COVID-19 infection may leave behind certain proteins, which can trigger the process that causes cortisol levels to drop. This results in increased inflammation and immune overreaction to stress.
The effect on cortisol may underlie many changes associated with long COVID, which has many neurological and neuropsychological symptoms, such as brain fog, anxiety, sleep disturbances, fatigue, depression, and post-traumatic stress disorder.




