Adults who use generative artificial intelligence (AI) tools every day—especially for personal, non-work reasons—show significantly higher rates of depression than those who use them less often or not at all, according to a new national survey of more than 20,000 people.
The findings, published Wednesday in JAMA Network Open, come as ChatGPT and similar tools have moved from novelty to daily routine for millions. The survey, conducted online in spring 2025, found that about one in 10 adults now use generative AI at least once a day.





