Prostate cancer screening isn’t just about a single prostate-specific antigen (PSA) number anymore. In 2025, we look at patterns over time, personal risk factors, and, when needed, advanced imaging. It’s a new era—one marked by precision, context, and choice.
Every week in my clinic, I meet men who are understandably confused by mixed medical messages. Some have heard the PSA test is outdated. Others worry about unnecessary treatment. Many don’t realize that modern screening is more than a blood test—it’s a toolkit. When used wisely, such a kit can catch aggressive cancers early while sparing men unnecessary procedures.
The Modern Prostate Cancer Screening Toolkit
A toolkit in plain language that explains what matters most and helps you or a loved one make an informed decision about screening contains the following five elements:
1. PSA Test
PSA is a protein made by the prostate that can be measured in the blood. Higher levels can be a warning sign of cancer—but they can also rise from harmless causes, such as an enlarged prostate or infection. That’s why a single “normal” or “abnormal” number doesn’t tell the whole story.
Dr. Manuj Agarwal
M.D.
Dr. Manuj Agarwal is a board-certified radiation oncologist and founder of Blue Wellth, a precision longevity and integrative medicine clinic dedicated to helping people extend their health span and live with vitality. With more than a decade of clinical experience, he blends advanced cancer care with cutting-edge approaches to aging and chronic disease prevention.