Osteoarthritis: Gene Study Finds New Drug Targets and Treatment Options

Researchers explore new strategies to treat progressive osteoarthritis.
Osteoarthritis: Gene Study Finds New Drug Targets and Treatment Options
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Current treatments for osteoarthritis—the top cause of disability around the world—relieve symptoms, but they don’t delay or reverse progression because they can’t address the underlying causes.

A recent German meta-analysis published in Nature may offer data to help improve the lives of people with osteoarthritis. Researchers identified 700 genes that could be involved in the etiology, or underlying causes, of the disease. Because these causes vary from person to person, this discovery could potentially lead to personalized treatments that target the biological factors contributing to the condition.

Findings from Genetic Testing

The causes of osteoarthritis involve an interplay between genetic and environmental factors, the study authors stated. To identify causes that might lead to more effective treatments, researchers examined the genetic makeup of more than 1.9 million people.
Mary West
Mary West
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Mary West is a freelance writer whose work has appeared in Medical News Today, Small Business Today Magazine, and other publications. She holds two bachelor of science degrees from the University of Louisiana at Monroe.