Study Links Autism to the Y Chromosome

New research analyzing more than 177,000 patients suggests the Y chromosome may increase autism risk.
Study Links Autism to the Y Chromosome
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Scientists have found a potential new explanation for why autism affects boys at nearly four times the rate of girls: The male sex chromosome itself may increase the risk.

In a new study published in Nature Communications analyzing data from more than 177,000 patients, researchers found that individuals with an extra male sex chromosome, the Y chromosome, were twice as likely to be diagnosed with autism spectrum disorder (ASD), while extra X chromosomes showed no such effect.

Understanding ASD and Sex Chromosomes

ASD is characterized by challenges in social interaction, communication, and behavior patterns, with boys being at significantly greater risk than girls. The reasons behind this disparity have long intrigued researchers.
George Citroner
George Citroner
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George Citroner reports on health and medicine, covering topics that include cancer, infectious diseases, and neurodegenerative conditions. He was awarded the Media Orthopaedic Reporting Excellence (MORE) award in 2020 for a story on osteoporosis risk in men.
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