Up to 60 percent of North American adults suffer from night-time leg cramps, a sudden painful contraction usually of the calf muscles that can last from a few seconds up to 10 minutes or more. Doctors do not know what causes most cases of leg cramps, but usually, they are not caused by dehydration or lack of minerals.
The leading theory is that most leg cramps come from the lack of a normal nerve reflex that causes a muscle fiber to relax when it is held in contraction. That is why people who suffer recurrent leg cramps should be checked for conditions that can cause nerve damage such as vitamin B12 deficiency or diabetes.
What Is a Muscle Cramp?
When you turn during sleep, you contract your calf muscles, which stretch their tendons. This stimulates nerve stretch receptors in the tendon and sends a message back to the spinal cord, telling the calf muscles to contract. After you contract a muscle, reflex messages are sent along nerves to the spinal cord to relax that muscle. If the message to relax is blocked, the muscle stays contracted and you develop a cramp. Cramping during sleep is usually due to an exaggeration of the normal muscle reflex that causes the muscle to stay contracted and hurt.What to Do When You Develop a Leg Cramp
When you get a leg cramp, you should gently try to walk it out while you massage the contracted muscle with your hands. Don’t put great force on the contracted muscle because you may tear it. If the cramp continues, apply cold compresses, which can relax the contracted muscle and numb the pain. Keep on gently massaging the muscle.Preventing Leg Cramps
You can often prevent night-time leg cramps if you:- Exhaust the stretch reflex before you go to bed by stretching your calf muscles.
- Apply a heating pad for 10 minutes before you go to sleep.
- Start a regular exercise program to strengthen your calf muscles. If you are a non-exerciser, the best exercise may be a stationary bicycle or a spinning class.
Work-Up for Frequent Leg Cramps
Most causes of leg cramps are harmless, but if you suffer frequent leg cramps, you need a detailed medical workup—check with your doctor.- All conditions that can cause blood vessel damage such as arteriosclerosis.
- Partially obstructed blood vessels.
- Pinched nerves in the back.
- Muscle damage.
- Nerve damage.
- Kidney disease.
- Abnormal mineral levels such as lack of potassium or calcium.
- Vitamin B12 deficiency.
- Abnormal hormone levels such as low thyroid.
- Diabetes.
- Dehydration.
- Medications such as birth control pills, diuretics (which are often prescribed for people with high blood pressure), steroids, raloxifene, and teriparatide, asthma medication such as albuterol, pain meds such as naproxen or pregabalin, statin drugs to lower cholesterol, and so forth (BMJ Clin Evid, 2015; 2015: 1113; Am Fam Physician, 2012, Aug 15;86(4):350-3).
- Up to 30 percent of nighttime leg cramps can be due to venous insufficiency or varicose veins. Vein specialists can do ultrasound evaluation of valves to see if they gap, allowing stretching of the vein to create contracture (cramp). This can be easily treated using laser or chemicals to close the inefficient valves or veins.




