HKBU Develops F-SLOH to Treat Alzheimer’s Disease

HKBU Develops F-SLOH to Treat Alzheimer’s Disease
A research team of The Hong Kong Baptist University led by Professors Li Min (C), Ricky Wong Man-shing (L), and Iyaswamy Ashok (R), discovers a multifunctional organic compound called F-SLOH with enormous potential to treat early Alzheimer's disease. Courtesy of Hong Kong Baptist University
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The Hong Kong Baptist University (HKBU) has developed a multifunctional organic compound called F-SLOH, which has the potential to treat early Alzheimer’s disease. The research results were published in the international academic journal “Redox Biology.”

Alzheimer’s disease is a neurodegenerative disease with common symptoms such as absent-mindedness, language impairment, being prone to losing direction, mood swings, and other behavioural problems. Alzheimer’s disease is the most common cause of dementia, accounting for 65% of the elderly Chinese with dementia in Hong Kong. On the global scale, in 2021, there were more than 55 million people who suffered from Alzheimer’s disease. There is currently no effective way to stop or reverse the course of the disease, only temporary relief of symptoms.

F-SLOH for Diagnosis and Treatment of Alzheimer’s Disease

The pathological features of Alzheimer’s disease are an abnormal accumulation of Aβ in brain nerve cells, excessive hyperphosphorylation of tau protein, and neuroinflammation, resulting in neuron reduction and cognitive dysfunction. Inhibition of abnormal accumulation of Aβ and excessive hyperphosphorylation of tau protein is regarded as the main and potentially effective method for the treatment of Alzheimer’s disease.
David Chu
David Chu
Author
David Chu is a London-based journalist who has been working in the financial sector for almost 30 years in major cities in China and abroad, including South Korea, Thailand, and other Southeast Asian countries. He was born in a family specializing in Traditional Chinese Medicine and has a background in ancient Chinese literature.
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