A 25-year study of nearly 28,000 people has upended common assumptions about cheese and brain health. Higher intake of high-fat cheese and cream was linked to a modestly lower long-term risk of dementia, while low-fat dairy and most other dairy products showed no clear link with dementia risk.
The Dairy Debate Isn’t Black and White
The research, published in Neurology, found that people who ate 50 grams or more of high-fat cheese daily had a slightly lower risk of dementia compared with those who ate less than 15 grams.Those who ate 20 grams or more of high-fat cream daily had a 16 percent lower risk than nonconsumers.
The protection was strongest against vascular dementia—the type caused by impaired blood flow to the brain. High cheese consumers had a 29 percent lower risk of this subtype, despite saturated fat’s well-established link to cardiovascular problems.
High-fat cream was also associated with a modestly lower overall dementia risk at 16 percent.
Of the 27,670 participants, about 10 percent developed dementia during the 25-year study period. Participants reported their diet at the start of the study using a food questionnaire, an interview, and a seven-day food diary.
In this study, high-fat cheeses are those that contain a fat content of 20 percent or more—such as Gouda, Brie, and cheddar. Creams with a fat content of 30 percent or higher were classified as high-fat cream, including whipping, clotted, and double cream.
The study is observational and cannot prove cause and effect, according to the researchers.
Why Cheese May Behave Differently Than Other Sources of Saturated Fats
Standard nutritional advice usually advises against high-fat dairy because it contains saturated fat. However, the new study indicates that not all fats are the same.“The food source of saturated fat matters,” Sonestedt said.
One possible explanation lies in the concept of the food matrix—that food is more than its individual components. Food contains different nutrients and structures, and they’re packed and interact differently, which affects how our bodies digest and metabolize food.
In cheese, fat, protein, calcium, and other bioactive compounds are bound within a complex matrix.
Fat in cheese is released slowly during digestion, leading to smaller and more gradual rises in blood fats after a meal. Firmer cheeses, she noted, tend to slow this process more than softer ones. Slower increases are easier on the vascular system—especially in the brain, which depends on a dense network of small vessels. Protecting these vessels may help reduce dementia risk.
Low-Fat Isn’t Simply High-Fat Minus the Fat
Removing fat from cheese doesn’t just reduce calories; it fundamentally alters the food itself. Low-fat versions of cheese have different textures and require different processing, which may reduce the availability of beneficial compounds.Dietary fat is needed for the body to properly absorb fat-soluble vitamins in the small intestine.
Processing matters increasingly when evaluating health outcomes. Minimally processed and fermented dairy foods are more often associated with neutral or beneficial cardiometabolic effects, while processed foods—characterized by refined ingredients and disrupted food matrices—are consistently linked to increased risk of obesity, Type 2 diabetes, cardiovascular disease, and all-cause mortality.
The cheeses commonly eaten in Sweden, where the study was done, are typically fermented and eaten uncooked—factors that may matter.
“Fermentation can produce bioactive peptides, and some cheeses contain fat-soluble vitamins such as vitamin K2,” Sonestedt said.
Context Matters More Than Any Single Food
The study found a higher dementia risk when participants replaced cheese with milk, fermented milk, processed meat, and high-fat red meat, echoing results from similar studies showing that swapping cheese for more processed foods may be a relatively healthier choice.However, this doesn’t mean that high-fat cheese is universally heart-healthy. While cheese may be a healthier option compared to less healthy foods, it does not mean that cheese is the optimal food for brain health.
Context matters, according to Sonestedt.
“Cheese eaten as part of regular meals within a balanced diet is very different from cheese consumed alongside processed meats or fast food,” she said.
“Keeping consumption of dairy foods relatively low and emphasizing healthy plant sources of protein and fat is a good overall strategy for health,” she told The Epoch Times.
While the study suggests that cheese may play a protective role within a balanced diet, dementia risk ultimately reflects the combined effects of diet and lifestyle over decades rather than the impact of any single food choice, Sonestedt said.







