FDA-Approved ALS Drug Fails Clinical Trial, Making Its Future Uncertain

The phase 3 clinical trial showed that the drug failed to improve patient symptoms after 48 weeks of treatment.
FDA-Approved ALS Drug Fails Clinical Trial, Making Its Future Uncertain
Amylyx Pharmaceuticals via AP
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Relyvrio, a drug meant to treat amyotrophic lateral sclerosis (ALS), failed clinical trials due to not providing significant symptom relief in those suffering from the disease.

In particular, the phase 3 clinical trial showed that the drug, which is a combination of sodium phenylbutyrate and taurursodiol, failed to improve patient symptoms after 48 weeks of treatment. Additionally, compared to a placebo, the medication was unable to significantly improve reported quality of life, overall survival, and respiratory function, CNN Health reported.
A.C. Dahnke
A.C. Dahnke
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A.C. Dahnke is a freelance writer and editor residing in California. She has covered community journalism and health care news for nearly a decade, winning a California Newspaper Publishers Award for her work.
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