7 Common Medications Harmful to Kidneys and Warning Signs of Renal Damage

Kidney disorders can be asymptomatic or we may simply not recognize the signs. Being able to identify the symptoms early may keep permanent damage at bay.

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The kidneys are intricately designed to play a crucial role in eliminating waste, excess fluids, and toxins produced within the body. However, despite their meticulous design, kidneys are fragile. People with conditions such as hypertension, diabetes, and autoimmune diseases in particular are highly susceptible to kidney damage.

Prolonged use of medications can also harm the kidneys. In this article, we will introduce seven categories of drugs and medications that may potentially cause kidney damage. Patients with health issues should exercise caution and use these medications under the direction of a physician.

7 Categories of Medications That May Harm the Kidneys

1. Anti-inflammatory and Analgesic Medications

ibuprofen, naproxen sodium, and acetaminophen medications that may harm the kidneys. These drugs provide analgesic and anti-inflammatory effects by suppressing the body’s inflammatory response. However, they can reduce blood flow to the kidneys, affecting their ability to filter toxins and remove excess fluid, leading to potential harm. Additionally, these medications can have adverse effects on the cardiovascular system. Therefore, if you are experiencing common headaches or fever, it is advisable not to hastily turn to these medications. Patients with chronic joint pain and persistent discomfort, in particular, should exercise caution due to the potential kidney damage associated with the long-term use of these medications.

2. Blood Pressure Medications

While lowering blood pressure is generally beneficial for the kidneys, prolonged use of certain blood pressure medications may increase the renal burden. Particularly, diuretics, when used excessively, can lead to decreased kidney blood flow, potentially resulting in kidney damage. Additionally, it is crucial to exercise caution when using angiotensin-converting enzyme inhibitors, especially in dehydrated conditions or when concurrently used with other medications, as it may contribute to kidney damage.

3. Antibiotics

Doctors sometimes inappropriately prescribe antibiotics for patients experiencing a cold or fever. However, these drugs are only effective against acute bacterial infections and have no impact on viral infections. Excessive use of antibiotics may lead to the development of antibiotic-resistant strains of bacteria. In such cases, certain antibiotics, such as vancomycin and aminoglycosides, may pose a risk of kidney toxicity.

4. Antiviral Drugs 

Patients with HIV/AIDS require the use of antiviral medications, typically in the form of therapy combining multiple drugs. This treatment approach can result in kidney damage, especially with prolonged use or higher doses, potentially leading to more severe adverse effects. Naturally, other antiviral medications may also present a similar concern.