Alzheimer’s disease affects about 5.3 million Americans. It’s the leading cause of dementia and the 6th leading cause of death in the U.S. And it’s growing at an alarming rate. Already 13% of people over 65 have been diagnosed with the disease. An astounding 43% of those over the age of 85 are victims.
Alzheimer’s has been called the defining disease of the boomer generation. Its victims are expected to triple by the year 2050.
In addition, it’s estimated that 10,000,000 others suffer with severe dementia and Parkinson’s disease.
But even if you escape these debilitating and life-threatening diseases, you may be among millions more who suffer from mild cognitive impairment (MCI or what is frequently called “age-related cognitive dysfunction”) and normal “age–associated memory impairment.” These conditions are what many of us have experienced as “senior moments.” The symptoms include memory loss, as well as a decline in the ability to think and reason.
Some of these problems are a result of the natural aging of our brains. But others arise from poor nutrition and exposure to environmental toxins.
Drugs have shown little promise and serious side effects. But here are seven proven methods to keep your brain young and sharp.
1. Bacopa Boosts Cognition
Bacopa monnieri (L.) is a traditional herb used for centuries in Ayurvedic medicine. It is prescribed as a memory and learning enhancer, a sedative, and anti-epileptic. In Australia, it is a popular memory aid for people over 60 years old.
Bacopa grows in the wet tropics and is also commonly known by its English name, water hyssop.
In a rigorous study published in the Journal of Complementary and Alternative Medicine, researchers found that Bacopa has positive effects on several measures of cognitive performance. In a randomized, double-blind, placebo-controlled clinical trial, they gave participants either 300 mg of Bacopa daily or a placebo pill. The subjects were 54 volunteers, 65 or older, without clinical signs of dementia.
After 12 weeks, those taking Bacopa improved their delayed recall memory, their reaction times and their ability to ignore irrelevant information. Placebo recipients saw no change.
In addition Bacopa recipients showed a decrease in heart rate, depression and anxiety while placebo recipients saw increases.
Bacopa’s memory-enhancing effects have been attributed in part to saponins. Other ways Bacopa may work include its antioxidant effects, protein synthesis in the brain, and modulation of brain stress hormones.
Other studies show Bacopa extracts also ameliorate neurotoxic effects of nicotine and aluminum, and reduce β-amyloid plaque levels in animals.
Ginkgo Biloba (Shutterstock*)
2. Ginkgo Biloba Improves Memory
For years gingko biloba has been linked to memory improvement. It acts as a free radical scavenger, protecting neurons from oxidation. It also improves microcirculation in the brain and reduces platelet aggregation.
Human studies show taking gingko biloba regularly can improve mental health, cognition, motor skills and quality of life. It’s particularly helpful for memory loss, attention, alertness, vigilance, arousal and mental fluidity.
In 2005 researchers put gingko biloba up against Pfizer’s $4 billion a year prescription drug donepezil (trade name Aricept) in a 24-week randomized, double-blind study. An extract of gingko biloba (160 mg per day) was found to be just as effective as the drug for mild-to-moderate Alzheimer’s disease. The researchers concluded there were no relevant differences in the efficacy of gingko biloba and donepezil, and use of both substances can be justified.
In a more recent double-blind trial gingko biloba was found to be significantly better than placebo in improving cognitive function and behavioral symptoms in 400 patients with Alzheimer’s disease or vascular dementia.
3. Tea, Wine and Chocolate Improve Thinking Skills
As we get older, a diet high in some flavonoid-rich foods may help with better thinking skills.
Researchers examined the relation between 3 common foods that contain flavonoids (chocolate, wine, and tea) and cognitive performance. They followed 2,031 participants aged 70 to 74 years from the Hordaland Health Study in Norway.
People who consumed chocolate, wine, or tea had significantly better scores on cognitive tests and lower rates of poor cognitive performance.
Those who ate all three foods had the best test scores and the lowest risks for poor test performance.
The good results were dose dependent. The best performance maxed out at 10 grams per day of chocolate and 75-100 ml per day of wine. The effect was most pronounced for wine and modestly weaker for chocolate.
Other research shows that resveratrol, found in wine and chocolate, has the ability to neutralize the toxic effects of proteins linked to Alzheimer’s disease.
In a study published in the Journal of Biological Chemistry researchers showed that resveratrol selectively targets and neutralizes clumps of peptides or proteins that are bad and have been linked to Alzheimer’s, but leaves alone those that are benign.
Resveratrol is a chemical compound in plants that acts as an antibiotic to fight off both bacteria and fungus. Besides grapes and cacao, it is found in raspberries, mulberries, blueberries, and cranberries. It’s also in peanuts, pine trees and Japanese knotweed, the source of most resveratrol supplements.
4. Antioxidants Decelerate Brain-Aging
It’s clear that people eating a diet high in fruits and vegetables have fewer age-related diseases like Alzheimer’s. Eating more high-antioxidant foods such as berries, Concord grapes, and walnuts may enhance cognitive and motor function in older people.
Studies show supplementing with fruit or vegetable extracts high in antioxidants (e.g. blueberries, strawberries, walnuts, and Concord grape juice) helps decrease the vulnerability to oxidative stress that occurs in aging. That can lead to improvements in behavior.
Fruits and vegetables can also enhance communication between neurons and decrease stress signals induced by oxidation and inflammation.
Other studies indicate that blueberry or Concord grape juice supplementation in humans with mild cognitive impairment increases verbal memory performance.
5. Intermittent Fasting Regenerates Brain
Overeating is a risk factor for many age-related diseases including cognitive impairment.
Experimental models of Alzheimer’s disease, Parkinson’s disease, Huntington’s disease and stroke show that dietary restriction (reduced calorie intake) can beef up the resistance of neurons in the brain to dysfunction and death.
How? Dietary restriction stimulates the expression of ‘stress proteins’ and neurotrophic factors. Neurotrophic factors may protect neurons by increasing production of proteins that suppress oxidation and free radicals.
In addition, dietary restriction increases the number of newly-generated neural cells in the adult brain. In other words, it may increase the brain’s capacity for plasticity and self-repair.