Weight-Loss Drug Carries Rare but Severe Stomach Risk, Including Pancreatitis: Study

Weight-loss drugs such as Wegovy and Ozempic may increase rare risks of pancreatitis, bowel obstruction, and gastroparesis.
Weight-Loss Drug Carries Rare but Severe Stomach Risk, Including Pancreatitis: Study
Boxes of the diabetes drug Ozempic rest on a pharmacy counter in Los Angeles on April 17, 2023. Mario Tama/Getty Images
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The new diabetes drug Ozempic, largely used for weight loss, and Wegovy, which is approved for chronic weight management in adults with obesity, have helped thousands of people lose weight, although recent evidence suggests that the medications may have rare but serious side effects.

In addition to common side effects such as nausea, vomiting, and diarrhea, some users have an increased risk of three rare—but very serious—stomach conditions, according to a research letter published on Oct. 5 in the Journal of the American Medical Association.
George Citroner
George Citroner
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George Citroner reports on health and medicine, covering topics that include cancer, infectious diseases, and neurodegenerative conditions. He was awarded the Media Orthopaedic Reporting Excellence (MORE) award in 2020 for a story on osteoporosis risk in men.
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