Synthesized Multifunctional Nanoparticles for Diagnosis and Treatment of Brain Glioma

Synthesized Multifunctional Nanoparticles for Diagnosis and Treatment of Brain Glioma
A research team led by Assistant Professor Wang Yi (pictured) of HKBU's Department of Chemistry, and Professor Law Ga-lai of PolyU's Department of Applied Biology and Chemical Technology has synthesized a novel near-infrared (NIR) persistent luminescent (PL) nanoparticle called TRZD, which can be used as a target for glioma, imaging diagnostic and therapeutic drug carrier. Courtesy of Baptist University
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A collaborative research team from Hong Kong Baptist University and Polytechnic University has synthesized a nanoparticle called TRZD, which can simultaneously diagnose and treat gliomas in the brain. The research results have been published in the international scientific journal Science Advances.

Gliomas are the most common primary brain malignancies, accounting for approximately one third of all brain tumors. Magnetic resonance imaging (MRI) is most commonly used for diagnosing gliomas. But due to its limited sensitivity (in the spatial resolution and short penetration depth), it is usually not able to detect cerebellar gliomas until after the appearance of clinical symptoms.

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