U.S. health agencies continue to recommend additional COVID-19 vaccine doses for children, yet research suggests booster vaccinations do not provide healthy children with additional immunologic protection against symptomatic infection.
A recently published study in Nature Medicine found that a third COVID-19 vaccine dose in healthy children aged 5 to 12 improved antibody titers but did not impact B cell memory or T cell responses, which are the most important predictors of protection against symptomatic SARS-CoV-2 infection.
