Research & Discoveries

Lipid Nanoparticles Cause Inflammation in Cells, but Damage Can Be Reduced: Penn Preprint

The study found that lipid nanoparticles cause inflammation by damaging cellular components called endosomes, but the degree of inflammation varies.
Lipid Nanoparticles Cause Inflammation in Cells, but Damage Can Be Reduced: Penn Preprint
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Marina Zhang
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A recent preprint from the University of Pennsylvania (Penn) showed that lipid nanoparticles, which transport COVID-19 mRNA in COVID-19 vaccines, cause inflammation within cells. However, this inflammation can be reduced if the proper lipid nanoparticle is used.

The researchers tested several different lipid nanoparticle formulations in animals, including ALC-0315 and SM-102, used in Pfizer’s and Moderna’s COVID-19 vaccines, respectively.
Marina Zhang
Marina Zhang
Author
Marina Zhang is a health reporter for The Epoch Times. She covers both health news and in-depth features on emerging health issues. Marina holds a bachelor's degree in biomedicine from the University of Melbourne. Contact her at [email protected].
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