Fresh and Frozen Embryo Transfer May Increase Risk of Leukemia Among Offspring

Other types of cancers are difficult to study because of their rarity in children.
Fresh and Frozen Embryo Transfer May Increase Risk of Leukemia Among Offspring
Lab worker immerses straw with embryo in tank of liquid nitrogen. YAKOBCHUK VIACHESLAV/Shutterstock
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Children born after medically assisted reproduction (MAR) are at an increased risk of developing leukemia, according to a recently published study in JAMA Network Open.

Among the more than 8.5 million children with a median age of 6.4 years born in France between 2010 and 2021, the overall risk of cancer was the same among those conceived naturally and those born after fresh embryo transfer (hazard ratio of 1.12), frozen embryo transfer (hazard ratio of 1.02), or artificial insemination (hazard ratio of 1.09). A hazard ratio compares the occurrence of an event between two groups. A hazard ratio of 1 indicates equal event occurrence between treatment and control groups.

Megan Redshaw
Megan Redshaw
J.D.
Megan Redshaw is an attorney and investigative journalist with a background in political science. She is also a traditional naturopath with additional certifications in nutrition and exercise science.