Many people may be aware that neutralizing antibodies significantly wane after only a few months following COVID-19 vaccination. Newly emerging subvariants have developed a solid ability to escape from neutralizing antibodies.
However, another significant facet of the COVID-19 vaccine is that it can damage our cellular immunity, especially T-cell immunity. Cellular immunity, or cell-mediated immunity, does not involve antibodies and is pivotal in preventing the severe form of COVID-19. Recent evidence shows that after a fifth vaccine booster dose, cellular immunity waned as well.
