Exercise May Protect the Liver From Booze

Exercise May Protect the Liver From Booze
HOPKINGTON, MA - APRIL 21: In this long exposure photograph, runner's shoes are seen at the beginning of the Boston Marathon on April 21, 2014 in Hopkington, Massachusetts. Today marks the 118th Boston Marathon; security presence has been increased this year, due to two bombs that were detonated at the finish line last year, killing three people and injuring more than 260 others. Photo by Andrew Burton/Getty Images
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Over time, excessive drinking can lead to several chronic conditions, such as fatty liver disease and cirrhosis. But there’s new evidence that aerobic exercise may protect the liver.

“Excessive alcohol consumption is one of the most common causes of chronic liver failure,” says Jamal Ibdah, professor of medicine and chair in cancer research at the University of Missouri School of Medicine.

“We know from previous research that chronic and binge drinking causes modifications to protein structures within the liver, resulting in irreversible damage. In our current study we wanted to see whether increased levels of aerobic fitness could prevent alcohol-related liver damage.”

For the study, published in the journal Biomolecules, researchers used rats bred for high activity, or “runner rats,” to test if increased metabolism protected the liver against fatty deposits and inflammation.

One group of rats was exposed to chronic alcohol use for six weeks and compared to a second group that was not exposed to alcohol during the same time period.

Higher physical activity levels seems to protect against the metabolic dysfunction that eventually leads to irreversible liver damage.