Colonoscopy: Unexpected Results From a Major Study, Is It Worth Doing?

Colonoscopies don’t save as many lives as previously thought.
Colonoscopy: Unexpected Results From a Major Study, Is It Worth Doing?
3D illustration of a body with intestinal polyp. peterschreiber.media/Shutterstock
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Although many view a colonoscopy as an uncomfortable or even scary procedure, around 15 million of them are carried out annually in the United States, and 60.6 percent of people aged 50 to 75 without a personal history of colorectal cancer have had one in the past 10 years.
It’s believed that a colonoscopy not only helps find cancer but also prevents cancer from developing from polyps. Because of its high level of sensitivity and specificity, colonoscopies have been regarded as the gold standard for colon cancer screenings for a long time.

Unexpected Result From a Major Colonoscopy Study

However, a major clinical study, the Nordic-European Initiative on Colorectal Cancer (NordICC) study published in 2022, raised questions about the efficacy of colonoscopies.
Yuwei Zhang, M.D., Ph.D.
Yuwei Zhang, M.D., Ph.D.
Author
Yuwei Zhang, M.D., Ph.D., MPH, MBA, has 20 years of experience in oncology and healthcare, including work for providers, payers, and pharma companies. Her paper on esophageal cancer is one of the top ten most cited papers in the field. She regularly gives talks at universities, has been invited to review manuscripts for top-tier medical journals, and has supported successful launches of top-performing drugs with expertise in lifecycle management, data strategy, and digital innovation.
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