Fasting to Reverse Diabetes

Fasting to Reverse Diabetes
More than a century ago, fasting was said to bring about the cure of diabetes, speedily arresting its development, and causing complete disappearance of all its manifestations in several days or weeks. (ShutterStock)
Michael Greger
4/30/2022
Updated:
3/22/2023

Currently nearly half a billion adults have diabetes, and a 50 percent increase is expected in another generation. I’ve got tons of videos on the best diets for diabetes, but what about no diet at all?

More than a century ago, fasting was said to bring about the cure of diabetes, speedily arresting its development, and causing complete disappearance of all its manifestations in several days or weeks. Even so, starvation is guaranteed to lead to the complete disappearance of you, if kept up long enough. What’s the point of fasting it away if it’s just going to come raging back as soon as you restart the diet that caused it in the first place? Might it be useful to kind of kickstart a healthier diet? Let’s see what the science says.

Type 2 diabetes has long been recognized as a disease of excess, a disease of the idle rich, by which they mean anyone that doesn’t practice sustained vigorous bodily exertion every day, and earning enough to regularly eat more than they need, so diabetes is preventable, but then maybe it’s also treatable. If we are dying of overeating, maybe we can be saved by undereating. Remarkably this was suggested about 2,000 years ago in an Ayurvedic text. Diabetics were encouraged to live like a saint, walk for oh, 800 to 900 miles, dig a pond, or live only on cow dung and cow urine.

That reminds me of the Rollo diet for diabetes proposed in 1797, composed of a diet of rancid meat. That was on top of the ipecac-like drugs he used to produce severe sickness and vomiting. Anything that produces sickness has a temporary effect in relieving diabetes by diminishing the quantity of food eaten—and his diet plan, congealed blood for lunch and spoiled meat for dinner, certainly had that effect.

Similar benefits were seen in diabetics during the siege of Paris in the Franco‐Prussian War, leading to the advice to “Mangez le moins possible;” eat as little as possible. This was formalized into the Allen Starvation treatment, considered to be the greatest medical advance in the treatment of diabetes prior to the discovery of insulin. Before insulin, there was The Allen Era.

He noted reports in the clinical literature of even severe diabetes clearing up on wasting diseases like tuberculosis; so, he decided to put it to the test. He found that even in the most severe type of diabetes, he could clear sugar from people’s urine within 10 days. Of course, that’s the easy part—it’s maintaining it once they start eating again, for which he stuck to two principles: keeping them underweight, and restricting the quantity of fat. A severe diabetic can be symptom-free for days or weeks, but add some butter or olive oil, and the disease can come raging back.

As I covered before, diabetes is a disease of fat toxicity. Infuse fat into people’s veins through an IV, and, by using a high-tech type of MRI scanner, you can show in real time the buildup of fat in muscle cells within hours, accompanied by an increase in insulin resistance. The same thing happens when you put people on a high-fat diet for three days, or even just one day…or even just a single meal can increase insulin resistance within six hours. Acute dietary fat intake rapidly increases insulin resistance. Why do we care? Because insulin resistance in our muscles in the context of too many calories leads to a buildup of liver fat, which leads to the buildup of fat in the pancreas, which is eventually what causes diabetes. Type 2 diabetes can now be understood as a state of excess fat in the liver and pancreas, and remains reversible for at least 10 years in most individuals.

Put people on a very low-calorie diet, 700 calories a day, and fat can get sucked out of your muscle cells, and you get a corresponding boost in insulin sensitivity. Fat is then sucked out of your liver, and if you keep it up the fat gets sucked out of your pancreas, and if you catch it early enough, that means a reversal of your type 2 diabetes, meaning normal sugars on a normal diet.

With the loss of 15 percent of body weight, nearly 90 percent of those who’ve had type 2 diabetes for less than four years can achieve remission, whereas it may only be reversible in 50 percent of those who’ve lived with the disease for longer than eight years. That’s better than bariatric surgery, where those losing even more weight only got 62 and 26 percent remissions. Your forks are better than surgeon’s knives. Here’s how much weight you have to lose to achieve various remission rates for those who’ve had diabetes for an average of three years. Lose about 30 pounds, and most newly-diagnosed type 2 diabetics can reverse their disease. So, an extended bout of physician-supervised, water-only fasting could get you there, but you have to maintain that weight loss. One of the things we can say with certainty is that if you regain the weight, you regain your diabetes.

To bring it full circle, the initial euphoria about “medicine’s greatest miracle,” the discovery of insulin in 1921, soon gave way to the realization that while it was literally a life-saver for type 1 diabetics, the use of insulin on its own in type 2 diabetics would not be enough to prevent the later onset of complications like kidney failure, blindness, stroke, amputations; so, as argued by one the most famous diabetes pioneers, Elliot Joslin, self-discipline on diet and exercise, as it was in the days prior to insulin, should be central to the management of diabetes.

Michael Greger, MD, FACLM, is a physician, New York Times bestselling author, and internationally recognized professional speaker on a number of important public health issues. He has lectured at the Conference on World Affairs, the National Institutes of Health, and the International Bird Flu Summit, testified before Congress, appeared on “The Dr. Oz Show” and “The Colbert Report,” and was invited as an expert witness in defense of Oprah Winfrey at the infamous “meat defamation” trial. 
Tis story was originally published on the NutritionFacts.org site
Michael Greger, MD, FACLM, is a physician, New York Times bestselling author, and internationally recognized professional speaker on a number of important public health issues. He has lectured at the Conference on World Affairs, the National Institutes of Health, and the International Bird Flu Summit, testified before Congress, appeared on “The Dr. Oz Show” and “The Colbert Report,” and was invited as an expert witness in defense of Oprah Winfrey at the infamous “meat defamation” trial. This article was originally published on NutritionFacts.org
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