The human brain goes through dramatic developmental changes in the first years of life. During this period it is particularly sensitive to environmental influences. This sensitivity helps babies learn and develop, but it also leaves them vulnerable to negative experiences, such as maltreatment, which can have a lasting physical and psychological impact.
In our latest research, published in PNAS, we show that extreme adversity early in life is linked to changes in brain structure in adulthood. Early childhood adversity experienced in institutions was related to a smaller brain as well as regional changes in brain structures. Some of these changes were linked to neurodevelopmental problems, such as attention deficit hyperactivity disorder (ADHD), which can arise following adversity.