Although the causes of Alzheimer’s disease remain a mystery, genetic research is now providing clues about how the disease develops.
We know that rare genetic mutations can cause early-onset Alzheimer’s; however, both genetic and environmental factors are involved in the more common late-onset form of the disease. By collecting information on the genetic makeup of thousands of people, scientists in our group, and others, have identified nearly 30 gene variants that are more common.
One of the biological functions implicated in Alzheimer's from these genetic findings is the transport of material into the cell, known as endocytosis.
