On August 31, 2022, the Food and Drug Administration (FDA) approved two new bivalent COVID-19 booster vaccines by Pfizer and Moderna respectively.
Both vaccines target the original virus strain, as well as the latest prevalent strains of Omicron—the BA.4 and BA.5 subvariants. These strains are currently responsible for almost all new cases of COVID-19 infection in the United States.