Scientific researchers are increasing finding causes of a variety of physical and emotional conditions that many people, including physicians, are unaware of, but which can have ripple effects throughout the body. One such condition is a mutation in the MTHFR gene that impairs the conversion of the homocysteine enzyme into methionine, another enzyme which plays many important roles to ensure our health. But the main point with a MTHFR gene mutation is that there will be excess homocysteine in the body, which among other possibilities, can increase the risk of cardiovascular disease, stroke, hardening of the arteries, and blood clotting.
There are a number of core symptoms most commonly observed with a MTHFR gene mutation. Marjie C. Andrejciw, in her article, “MTHFR Gene as Related to Chronic Illness” (Hawthorn University Lecture Series), lists the following symptoms - chronic pain, depression, anxiety, insomnia, sensitivity to chemicals, medication intolerance, weakened immune system, addictions, infertility, and elevated homocysteine levels.
Mutations in the MTHFR gene can compromise the ability of our body to eliminate toxins and increase oxidative stress, which ultimately results in inflammation and the breakdown of body tissue. The MTHFR gene mutation has been associated with a number of conditions, including autism, ADHD, bipolar disorder, panic attacks, chronic fatigue syndrome, fibromyalgia, autoimmune disorders, migraines, thyroid problems, Irritable Bowel Syndrome, hypertension, schizophrenia, and dementia. Problems related to pregnancy also have been reported including miscarriages, stillbirths, pre-eclampsia, and neural tube defects. Pre-eclampsia is associated with high blood pressure and organ damage, usually to the kidneys. For a complete list of conditions associated with the MTHFR gene mutation, refer to www.journeyofhealth.org.
