Almost 200 Cases of Mystery Hepatitis in Children Worldwide, Reaching Canada and Japan: Reports

Almost 200 Cases of Mystery Hepatitis in Children Worldwide, Reaching Canada and Japan: Reports
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Around 200 cases of mysterious acute hepatitis—sudden-onset liver disease of unknown origin—in children have been confirmed in recent months across over a dozen countries around the world. Similar such cases have also in recent days been reported in Canada and Japan.

These cases of hepatitis involve children aged 1 month to 16 years old, many of whom suddenly developed gastrointestinal symptoms including abdominal pain, diarrhea, and vomiting, before coming down with jaundice (yellowing of the skin and eyes), and severe acute hepatitis, the World Health Organization (WHO) said on April 23. Most of the cases did not have a fever. WHO also noted that none of the cases had any of the five common hepatitis viruses—A, B, C, D and E.

Most Cases in Europe

Andrea Ammon, the director of the European Centre for Disease Prevention and Control (ECDC), told reporters in a virtual briefing on April 26 that at least 190 cases of unexplained acute hepatitis in children have been reported around the world, with 140 of them in Europe. Most of the European cases—at least 110—come from the United Kingdom, mostly in children under 10 years old.