DOJ Announces Largest Fentanyl Bust in US History Targeting Operation Led by Sinaloa Cartel

Of the 16 people arrested in the operation, six are in the United States illegally.

Posters showing seized drugs before Attorney General Pam Bondi held a press conference at the Treasury Department in Washington on May 6, 2025. Oliver Contreras/AFP via Getty Images

The Department of Justice (DOJ) on Tuesday announced the largest fentanyl bust in U.S. history.

The major drug bust marked “the most significant victory in our nation’s fight against drug trafficking,” Attorney General Pam Bondi said during a press conference at the DOJ.