LOUISVILLE, Ky.—Tyler Shough threw for 349 yards and two touchdowns as No. 22 Louisville cruised to a 49–14 victory over Jacksonville State on Saturday.
It was the sixth time the seventh-year signal caller threw for more than 300 yards in a game. Shough, who completed 21 of 33 attempts, put the game away with a 48-yard touchdown pass to Chris Bell that gave the Cardinals (2–0) a 35–14 lead with 8:58 left in the third quarter. He added another midway through the fourth quarter and then was pulled.
