Thairo Estrada’s Go-ahead 3-run Homer in the Fifth Inning Lifts Giants Past Rockies 10–5

San Francisco Giants' Thairo Estrada (39) celebrates after hitting a three-run home run against the Colorado Rockies that scored LaMonte Wade Jr. (31) and Jorge Soler, second from left, during the fifth inning of a baseball game in San Francisco on May 17, 2024. Jeff Chiu/AP Photo

SAN FRANCISCO—Thairo Estrada hit a go-ahead three-run homer in the fifth inning and singled twice, Luis Matos drove in a career-high five runs and the San Francisco Giants beat the Colorado Rockies 10–5 on Friday night for their sixth straight victory at home in the series.

Matos and Matt Chapman had three hits apiece for a refreshed San Francisco squad coming off its first off day following 16 straight games.