Week 1 of the 2025 NFL season saw Brock Purdy of the San Francisco 49ers get injured, and he was unable to suit up in Week 2. However, Week 2 was much more harmful to the QB position, as several signal callers went down, leaving their teams scrambling. Four notable quarterbacks suffered injuries, including some of the biggest names in the sport.
Joe Burrow, Jayden Daniels, Justin Fields, and J.J. McCarthy all suffered injuries that could keep them sidelined. Even MVP Josh Allen briefly had to leave his team’s game due to a nose injury, only to then return.