Daniel Simmons, 38, died in the fire on Rainbow Road in Cool Ridge, Raleigh County early Tuesday.
His wife was arrested on Monday by State Police after officers discovered a clandestine meth lab at the house.
Danita Simmons later admitted to making meth with her husband at the house once a week, according to the criminal complaint obtained by WVVA.
Daniel Simmons was at-large at the time of his death.
The cause of the fire is still undetermined.
The Simmons have three sons and three daughters.