Stanton reached the milestone in his 1,341st career game when he hit a two-run homer off Tyler Wells four batters in. He entered the night with four hits in his previous 31 at-bats and no homers in his prior 14 games.
Stanton joined Alex Rodriguez and Babe Ruth as the third player to get his 350th career homer with the Yankees. He helped the Yankees win their fifth straight and seventh in the last eight games.
Anthony Santander hit a tying two-run homer in the sixth for the Orioles, who dropped their third straight.
White Sox 7, Royals 3
Andrew Vaughn belted a tiebreaking three-run home run in the seventh inning and Jake Burger added his own homer as Chicago defeated visiting Kansas City to end an eight-game losing streak.
Chicago scored four unanswered runs after the Royals’ Whit Merrifield tied the game 3–3 with a sacrifice fly in the seventh inning. Vaughn connected on the first pitch he saw from Scott Barlow, who entered after Collin Snider (2–1) allowed consecutive two-out singles.
Bennett Sousa (1–0) notched the win after pitching just two-thirds of an inning, and Kendall Graveman struck out four to notch a two-inning save.
Cardinals 10, Mets 5
Nolan Arenado drove in three runs before getting ejected and St. Louis rallied past visiting New York in a contentious game.
Corey Dickerson and Dylan Carlson drove in two runs each as the Cardinals erased a 4–1, second-inning deficit and snapped their three-game losing streak.
The benches and bullpens emptied in the bottom of the eighth inning after Arenado became enraged by Yoan Lopez’s up-and-in pitch. Things escalated after Arenado shoved Tomas Nido, the Mets’ catcher, to earn an ejection. Cardinals coach Stubby Clapp wrestled Mets slugger Pete Alonso to the ground. Clapp was also ejected.
Diamondbacks 3, Dodgers 1
Arizona scored twice in the eighth inning to beat Los Angeles in the rubber match of a three-game series in Phoenix.
Nick Ahmed homered for the Diamondbacks, who recorded their first series win against the Dodgers since Aug. 29–Sept. 1, 2019. Ian Kennedy (2–1) earned the victory and Mark Melancon retired the Dodgers in order in the ninth for his fourth save.
After Los Angeles tied the score at 1 on Trea Turner’s RBI single in the top of the eighth, Arizona’s Daulton Varsho drew a leadoff walk from Daniel Hudson (1–1) and scored when Sergio Alcantara bunted to third baseman Max Muncy, whose errant throw to first sailed into right field. Arizona added an insurance run on Pavin Smith’s groundout.
Cubs 6, Braves 3 (10 innings)
Patrick Wisdom’s two-run homer capped a three-run, 10th-inning rally as Chicago won at Atlanta.
The Cubs greeted Braves reliever Tyler Matzek (0–1) with an RBI double by Willson Contreras to open the 10th inning. Two batters later, Wisdom hit a 3–2 pitch over the center field fence for his third homer.
David Robertson (1–0) pitched 1 1/3 innings and struck out three for the win. Rowan Wick tossed a scoreless 10th inning to earn his first save.
Rays 3, Mariners 2
Kevin Kiermaier hit a two-run home run in the fourth inning and Drew Rasmussen pitched six scoreless innings as the Rays defeated Seattle in St. Petersburg, Fla.
Rasmussen (1–1) gave up only two hits and had his longest outing of the season. He threw a career-high 84 pitches and struck out nine.
Seattle’s pitching plans were scrambled almost from the beginning of the game. Starter Marco Gonzales (1–2) faced only three batters and threw 11 pitches before he was forced to leave the game after being struck on his pitching wrist by a line drive off the bat of Harold Ramirez.
Brewers 3, Pirates 1
Tyrone Taylor singled home the go-ahead run in the seventh inning and five Milwaukee pitchers combined on a one-hitter in a win over host Pittsburgh.
Brewers starter Aaron Ashby pitched 5 2/3 innings, giving up one run and one hit with five walks and six strikeouts. Trevor Gott (1–0), who struck out the only batter he faced, Brad Boxberger, Devin Williams and Josh Hader followed. Hader walked two but struck out three in the ninth for his 10th save.
Pirates reliever Wil Crowe (1–1) gave up two runs, one earned, and three hits in one inning.
Astros 4, Rangers 3
Cristian Javier pitched effectively in his first start of the season and Kyle Tucker delivered a bases-clearing double that keyed Houston to a victory in Arlington, Texas.
Javier (1–0) tossed a season-high 84 pitches before the four-man bullpen completed what he started. Bryan Abreu struck out Adolis Garcia to close the sixth inning with the tying run on base. Ryne Stanek allowed a run in the ninth but stranded the tying run at third for his first save.
Texas’ Mitch Garver socked a solo homer and singled, and Kole Calhoun also had two hits.
Angels 9, Guardians 5
Taylor Ward finished a single shy of hitting for the cycle, helping lift Los Angeles past Cleveland in Anaheim, Calif., for its fourth straight win.
Ward doubled leading off the first inning, hit a grand slam in the second, walked in the fourth and tripled in the sixth. Shohei Ohtani (2–2) picked up the victory, giving up only a first-inning, two-run home run to Jose Ramirez during his five-inning stint.
Cleveland, which has lost six in a row, finished with 11 hits, including another two-run homer by Ramirez in the eighth inning.
Athletics 1, Giants 0
Chad Pinder hit the sixth pitch of the game for a home run and local product Paul Blackburn made his first start at Oracle Park a memorable one as Oakland edged host San Francisco.
Reinstated from the COVID injured list before the game and immediately penciled into the top of the Oakland lineup, Pinder took Giants opener Sam Long deep for his third home run of the season.
Blackburn (3–0) and five relievers made the run stand up, with the 28-year-old right-hander leading the way with five innings of three-hit ball.
Padres 8, Reds 5
Jurickson Profar connected for a three-run homer and MacKenzie Gore struck out 10 in his third career start as visiting San Diego continued its mastery of Cincinnati.
Eric Hosmer extended his blistering start with two hits, including a tape-measure homer to right, and two walks. Hosmer is leading the National League in batting at .410. The Padres have won all five meetings between the clubs this season entering the series finale on Thursday.
Tommy Pham and Brandon Drury homered and Kyle Farmer matched a major league record with four doubles for the Reds, who lost for the 13th time in 14 games.
Phillies 7, Rockies 3
Odubel Herrera homered, hit a sacrifice fly and drove in two runs, Bryce Harper added three hits and host Philadelphia defeated Colorado.
Didi Gregorius contributed two hits, a sacrifice fly and two RBIs for the Phillies, who won their third in a row in this four-game series. It was the 1,000th career game at shortstop for Gregorius. Garrett Stubbs, Nick Castellanos and Alec Bohm also had two hits each.
C.J. Cron homered and Jose Iglesias went 4-for-4 for the Rockies. Elias Diaz and Randal Grichuk chipped in with two hits apiece. In his season debut, Rockies starter Ryan Feltner (0–1) tossed five innings and allowed seven hits and four runs.
Red Sox 7, Blue Jays 1
Michael Wacha allowed one run in six innings, Xander Bogaerts was 4-for-4 with a walk and an RBI and visiting Boston defeated Toronto.
Enrique Hernandez had two RBIs for the Red Sox, who ended a four-game losing streak while taking the third game of a four-game series. Wacha (2–0) allowed four hits and two walks with five strikeouts.
Toronto starter Ross Stripling allowed one run and five hits while striking out seven in five innings. He retired his final eight batters, six on strikeouts before Trent Thornton (0–1) replaced him in the sixth and allowed two runs.
Twins 5, Tigers 0
Max Kepler hit two solo home runs, Joe Ryan pitched seven dominant innings and Minnesota stretched its winning streak to six games by blanking Detroit in Minneapolis.
Kepler, who also homered in the series opener on Tuesday, has 12 career multi-homer games. Minnesota’s Ryan Jeffers supplied a two-run homer and RBI double, while Trevor Larnach doubled twice and scored two runs. Ryan (3–1) walked one and struck out nine.
Detroit starter Michael Pineda (1–1) gave up four runs on seven hits in five innings. He struck out two without issuing a walk as the Tigers dropped their fourth straight.
Marlins 2, Nationals 1
Jesus Aguilar homered, Pablo Lopez threw six scoreless innings and visiting Miami defeated slumping Washington for its fourth straight win.
Lopez (3–0) allowed three hits, walked one and struck out six while lowering his ERA to 0.39. He has tossed 18 1/3 scoreless innings while winning his past three starts. Anthony Bender pitched 1 1/3 innings for his fourth save.
Maikel Franco had two hits for the Nationals, who have lost seven straight games and have scored three runs or fewer in each of their past eight games.