The Blues and Lions will face off on March 15 in Ellis Park in Johannesburg, South Africa.
Kick-off for the Super Rugby game is scheduled for 3 p.m. local time (midnight on Sunday AEDT).
The game will be broadcast live on Fox Sports 2 in Australia, Sky Sports in New Zealand, SuperSport in South Africa, and Sky Sports 2 in the United Kingdom.
Live streaming is available via SANZAR for areas outside of this.
Early predictions have the Blues winning by 6.
See lineups below:
SHARKS: SP Marais, JP Pietersen, S’bura Sithole, Frans Steyn, Lwazi Mvovo, Patrick Lambie, Cobus Reinach, Ryan Kankowski, Willem Alberts, Marcell Coetzee, Stephan Lewies, Anton Bresler, Jannie du Plessis, Bismarck du Plessis (c), Tendai Mtawarira.
Reserves: Kyle Cooper, Dale Chadwick, Lourens Adriaanse, TBC, Tera Mtembu, Charl McLeod, Heimar Williams, Jaco van Tonder.
REDS: Queensland: Aidan Toua, Rod Davies, Chris Feauai-Sautia, Mike Harris, Lachie Turner, Quade Cooper, Will Genia; Jake Schatz, Liam Gill, Ed Quirk, James Horwill, Rob Simmons, Greg Holmes, Saia Fainga’a, James Slipper.
Reserves: James Hanson, Ben Daley, Jono Owen, Ed O’Donoghue, Beau Robinson, Nick Frisby, Ben Tapuai, Dom Shipperley.