A new Ebola outbreak is spreading in central Africa, prompting officials around the world to take precautions to try to avoid the disease from entering their countries.
The outbreak is centered in Congo, a mostly landlocked country with a population of about 109 million people. Congolese authorities on May 19 said they suspect the outbreak has caused 136 deaths, and around 543 cases of Ebola.
Ebola is a disease that causes a range of symptoms, including fever and internal bleeding.
The disease has an average mortality rate of about 50 percent.
Believed to Have Started Weeks Ago
The person believed to be the index patient died on April 20, Congolese health officials told the World Health Organization (WHO) this week.Congo’s health minister, Samuel Roger Kamba, told other government officials during a May 19 meeting that the person was “probably already infected well before” officials learned about the case, and an investigation is underway.
The coffin holding that person was damaged, Kamba told a separate briefing later Tuesday. The person was placed in another coffin. It was “from this funeral ceremony that the virus exploded,” he said.

Dr. Anne Ancia, the representative for the World Health Organization (WHO) in Congo, told reporters on Tuesday that “we don’t have yet all the epidemiological link[s] to be able to say when this outbreak [started], what is the patient zero, or the index case.”
Spread Undetected for Weeks
The Bundibugyo virus spread undetected for at least a few weeks, health experts and aid workers said.“Because early tests looked for the wrong strain of Ebola, we got false negatives and lost weeks of response time,” said Matthew M. Kavanagh, director of the Georgetown University Center for Global Health Policy and Politics. “We are playing catch-up against a very dangerous pathogen.”
The first confirmation of Ebola did not come until May 14.

“The situation is quite worrying and is evolving pretty quickly,” Esther Sterk from the Medecins Sans Frontieres aid group said. “It was detected quite late.”
Caused by Virus
Ebola is caused by orthoebolaviruses. The orthoebolavirus behind the current outbreak is the Bundibugyo virus, according to testing completed in Congo and Uganda.No vaccines or treatments are available for the Bundibugyo virus.
Ervebo, a vaccine cleared for another Ebola virus, may end up being used for the outbreak, but “it would take two months for it to be available,” Ancia, the WHO’s representative, said on May 19.
Vasee Moorthy, a WHO senior adviser, indicated in a briefing on May 20 that it is possible to reformulate the vaccine to target Bundibugyo, but no doses are available, and it would take six to nine months to start testing the shot.
Merck, which manufactures Ervebo, did not respond to requests for comment.

Another candidate vaccine, developed by Oxford University and Serum Institute of India, could be available for trials in two to three months, but there is no preclinical data for the vaccine as of yet, according to Moorthy.
Congo was expecting shipments from the United States and the UK of an experimental vaccine for different types of Ebola, developed by researchers at Oxford, Jean-Jacques Muyembe, a virus expert at the National Institute of Biomedical Research, told reporters on Tuesday.
Scale of Outbreak
There have been 51 confirmed cases in the new outbreak, but the scale of the epidemic is “much larger,” Tedros Adhanom Ghebreyesus, WHO’s director-general, said on Wednesday.“Beyond the confirmed cases, there are almost 600 suspected cases and 139 suspected deaths,” he said. “We expect those numbers to keep increasing, given the amount of time the virus was circulating before the outbreak was detected.”
Dr. Craig Spencer, an associate professor at the Brown University School of Public Health, who survived Ebola more than a decade ago after contracting the disease in Guinea, said that Ebola is “a disease of compassion” because “it impacts the people who are more likely to be taking care of sick folks.”

He added, “I suspect that the number of cases is going to go up pretty dramatically in the coming weeks as we do better surveillance and end up finding there were a lot more cases and probably a lot more deaths than we recognized.”
Although more than 20 Ebola outbreaks have taken place in Congo and Uganda since 1976, this is only the third time that the Bundibugyo virus has been detected.
Other Countries Take Action
Ugandan authorities said there was no evidence that Ebola was spreading within the country, and said that surveillance has been heightened along its border with Congo.Rwanda, which also neighbors Congo, closed its land border with the country over the weekend.

The order was imposed to try to prevent the introduction of Ebola into the country, officials said.







