Every time you make a memory, somewhere in your brain a tiny filament reaches out from one neuron and forms an electrochemical connection to a neighboring neuron.
The filaments that make these new connections are called dendritic spines and, in a series of experiments described in the Journal of Biological Chemistry, a team of researchers reports that a specific signaling protein, Asef2, a member of a family of proteins that regulate cell migration and adhesion, plays a critical role in spine formation.
