The 29-year-old Roddick, ranked 33rd in the world, is now 7-10 this season and has lost two of his three Grand Slam matches in 2012.
The French-born Mahut converted all seven of his break-point opportunities while Roddick was able to convert just three of his ten break-point chances. In the first set alone, Roddick was unable to convert any of his five opportunities while Mahut capitalized on his lone chance to win the set.
The 30-year-old Mahut hit 42 winners on the day to Roddick’s 26 and served up 13 aces to Roddick’s 8.
With the loss, the French Open remains the only Grand Slam event in which Roddick has failed to advance to at least the quarterfinals.
The Epoch Times publishes in 35 countries and in 19 languages. Subscribe to our e-newsletter.