49ers Use Defense, Deebo Samuel to Beat Rams 24–9

Wide receiver Deebo Samuel (19) of the San Francisco 49ers rushes for a touchdown as he breaks a tackle by cornerback Jalen Ramsey (5) of the Los Angeles Rams during the second quarter at Levi's Stadium in Santa Clara, Calif., on Oct. 3, 2022. Thearon W. Henderson/Getty Images

SANTA CLARA, Calif.—Deebo Samuel turned a short catch into an electric 57-yard touchdown, Talanoa Hufanga returned an interception for a score and the San Francisco 49ers beat the Los Angeles Rams 24–9 on Oct. 3.

Jeff Wilson Jr. also scored on a 32-yard run that gave the Niners (2–2) their seventh straight regular-season win over their in-state rivals.