While the announcement was made initially in a comedic manner, eliciting laughter from the audience, Letterman highlighted his effort to protect the names of his staff members involved.
"The creepy stuff was that I have had sexual relations with women who work for me on this show. Now, my response to that is yes I have. " Letterman said.
"Would it be embarrassing if it were made public? Perhaps it would. Especially for the women…but that is a decision for them to make if they want to go public and talk about the relationships, if I want to go public and talk about the relationships, but what you don’t want is some guy saying…’I would like $2 million dollars or I am going to make trouble for you.’”
Letterman married long-time girlfriend Regina Lasko, earlier this year, and has a 5 year old son with her.
The announcement comes at a crucial time in late night television as the host of "The Tonight Show," Jay Leno, handed off the position to Conan O’Brien in June, transitioning to a 10pm primetime slot.
Since the NBC late night handoff Letterman has led in the ratings.










